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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Differential composition of DHA and very-long-chain PUFAs in rod and cone photoreceptors
|
|---|---|
| Published in |
Journal of Lipid Research, July 2018
|
| DOI | 10.1194/jlr.m082495 |
| Pubmed ID | |
| Authors |
Martin-Paul Agbaga, Dana K Merriman, Richard S Brush, Todd A Lydic, Shannon M Conley, Muna I Naash, Shelley Jackson, Amina S Woods, Gavin E Reid, Julia V Busik, Robert E Anderson |
| Abstract |
Long chain polyunsaturated fatty acids (LC-PUFA; C20-C22) are highly enriched in vertebrate retina and testes, where they are further elongated to very long chain PUFA (VLC-PUFA; C≥28) by Elongation of Very Long Chain Fatty Acids-4 (ELOVL4). These fatty acids play essential roles in modulating neuronal function and health. To better understand the role of LC-PUFA and VLC-PUFA in the retina, we investigated the lipid compositions of whole retinas or photoreceptor outer segment (OS) membranes of rod- and cone-dominant retinas. Fatty acid methyl esters and glycerophospholipid molecular species were analyzed by GC-MS/GC-FID and ESI-MS/MS, respectively. We found that whole retinas and OS from rod-dominant animals have higher amounts of LC-PUFA and VLC-PUFA than do cone-dominant retinas. The retinas and OS from the cone-dominant retinas also have lower amounts of di-DHA (22:6/22:6) molecular species in phosphatidylcholine, phosphatidylethanolamine, and phosphatidylserine, than do rod-dominant retinas. Since PUFA are necessary for optimal G-protein-coupled receptor signaling in rods, these findings suggest that cones may not have the same lipid requirements as rods. |
X Demographics
The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 33% |
| Brazil | 1 | 11% |
| United Kingdom | 1 | 11% |
| Unknown | 4 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 67% |
| Science communicators (journalists, bloggers, editors) | 2 | 22% |
| Scientists | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 36 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 28% |
| Researcher | 9 | 25% |
| Student > Master | 4 | 11% |
| Student > Doctoral Student | 2 | 6% |
| Unspecified | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 8 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 10 | 28% |
| Medicine and Dentistry | 5 | 14% |
| Chemistry | 4 | 11% |
| Agricultural and Biological Sciences | 3 | 8% |
| Neuroscience | 2 | 6% |
| Other | 3 | 8% |
| Unknown | 9 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 43. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2018.
All research outputs
#962,760
of 25,394,764 outputs
Outputs from Journal of Lipid Research
#99
of 4,811 outputs
Outputs of similar age
#20,502
of 339,750 outputs
Outputs of similar age from Journal of Lipid Research
#7
of 64 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,811 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,750 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.